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VAUTHEY, Professor Jean-Nicolas


Dr. Vauthey is Professor of Surgery Chief of the Hepato-Pancreato-Biliary Section and the Dallas/Fort Worth Living Legend Chair of Cancer Research .  Dr. Vauthey’s clinical research focuses on methods to measure and to improve outcome after hepatic resection for hepatobiliary malignancies.  Dr. Vauthey proposed a standardized method for calculating the volume of the anticipated liver remnant prior to major liver resection.  This method of measurement is used to compare patients prior to extended liver resection to determine the need for preoperative portal vein embolization.  Dr. Vauthey created the International Cooperative Study Group for Hepatocellular Carcinoma.  The group critically analyzed the staging system for hepatocellular carcinoma and questioned its complexity.  Based on this work, the American Joint Committee on Cancer and the International Union Against Cancer adopted a new simplified staging system for hepatocellular carcinoma.  Dr. Vauthey is the Chair of The American Joint Committee on Cancer Hepatobiliary and Pancreas Task Force for the 8th Edition of the Manual for Staging Cancer.  Dr. Vauthey has evaluated the use of preoperative chemotherapy in the multidisciplinary treatment of patients with colorectal liver metastases.  He is the author of a treatment algorithm for hepatic colorectal liver metastases. Dr. Vauthey most recent research focuses on the evaluation of the biology of colorectal liver metastases. Dr. Vauthey and his research team have shown that 6 mutated genes in 5 cancer pathways predict the outcome and prognosis of Stage IV colorectal cancer. These findings have implications for surgical treatment and surveillance after liver resection for liver metastases. Based on this work, the surgical approaches to patients with metastatic colorectal cancer can be personalized based on unique cancer biology features. Dr. Vauthey with his colleagues have recently developed a fast track treatment of colorectal liver metastases combining radiological and surgical procedures in a single hybrid room with state of the art surgical and imaging technology.


Dr. Vauthey has been an invited speaker at many major national and international meetings, including the postgraduate courses of the Society for Surgery of the Alimentary Tract, the American College of Surgeons, and the Society of Surgical Oncology.  Dr. Vauthey organized and moderated symposia at national and international meetings (Society of Surgical Oncology, American College of Surgeons, International Hepato-Pancreato-Biliary Association).  Dr. Vauthey is the Past President of the Americas Hepato-Pancreato-Biliary Association and the current President of the Society for Surgery of the Alimentary Tract the premier academic surgical society focusing on the study of digestive diseases.  Dr. Vauthey co-authored more than 600 publications in peer-reviewed journals and more than 85 reviews and book chapters in major textbooks.  Dr. Vauthey is editor or co-editor of major textbook devoted to hepatobiliary and pancreatic cancers.  Dr. Vauthey organized and chaired Consensus Conferences on Colorectal Liver Metastases and Resectable and Borderline Resectable Pancreas Cancer jointly sponsored by the American Hepato-Pancreato-Biliary Association, Society for Surgery of the Alimentary Tract, and Society of Surgical Oncology.  Dr. Vauthey is a reviewer for major surgical and medical journals.  He is on the editorial board of major journals including the Journal of the American College of Surgeons and Annals of Surgery. Dr. Vauthey is Associate Editor of Digestive Surgery.

Dr. Vauthey is the recipient of multiple awards including the prestigious 2011 Faculty Achievement Award in Patient Care for his commitment to the mission of The University of Texas MD Anderson Cancer.

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