Professor Reynolds is Academic Head of Clinical Surgery at St. James’s Hospital and Trinity College Dublin. He is the National Lead in Ireland for oesophageal and gastric cancer. He is Cancer Lead at the Trinity St James’s Cancer Institute, and a Principal Investigator in the Trinity Translational Medicine Institute. He is President of the Irish Society of Clinical Nutrition and Metabolism (IRSPEN). He has formerly held Fellowship positions with the University of Pennsylvania and Wistar Institute in Philadelphia and at the Memorial Sloan-Kettering Cancer Centre in New York. He was a Senior Lecturer at St. James’s University Hospital in Leeds (1994-6).
Professor Reynolds has obtained numerous research awards and has published widely in cancer research, with over 400 publications and approximately €5m research grant income.
His clinical interest is in diseases of the oesophagus and stomach. His research interest is in six principal areas: (1) pathogenesis of Barrett’s oesophagus and progression; (2) prediction of response and resistance to chemotherapy and radiation therapy; (3) obesity, non-alcoholic fatty liver disease, altered metabolism, and cancer; (4) malnutrition and peri-operative nutrition; (5) multimodal enhanced recovery after surgery (ERAS) pathways; and (6) cancer clinical trials, he is PI for the NeoAEGIS RCT in oesophageal adenocarcinoma.