Professor James is Professor of Prostate and Bladder Cancer Research at the Institute of Cancer Research and the Royal Marsden Hospital, London. He was previously Professor of Clinical Oncology in Birmingham up until 2019. He is also an NIHR Senior Investigator and Deputy Dean of the Institute of Cancer Research.
His research is focussed on advanced prostate cancer and on bladder preservation in locally advanced disease. Prof. James is Chief Investigator on the ground-breaking STAMPEDE trial, which has been used to evaluate, to date, 10 different therapies for advanced prostate cancer in more than 11,000 men. The trial has shown that big survival gains can be made by using existing treatments in novel settings.
In the bladder cancer field, Prof James has led a series of trials of chemoradiotherapy that demonstrated that low dose synchronous chemotherapy reduced invasive bladder cancer relapse rates by 43%, defining chemoradiotherapy as the standard of care for bladder preservation.