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Professor and Consultant in Medical Oncology, University of Sheffield and Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK


Professor Hussain is Professor and Consultant in Medical Oncology at the University of Sheffield and Sheffield Teaching Hospitals NHS Trust. His major areas of interest are management of urological cancers, clinical trials, early drug development and translational medicine. He has set up many clinical trials from early phase to late phase studies during his career. His work on organ preservation in bladder cancer moved all the way from an early Phase I study (Hussain S et al. Annals of Oncology 2001), to a Phase II efficacy study (Hussain S et al. Br J Cancer 2004) that led to a Cancer Research UK funded study BC2001 (James ND et al. N Eng J Med 2012). This study has now changed the standard of care for patients with muscle invasive bladder cancer opting for organ preservation treatment.

Professor Hussain is Principal Investigator of several studies in urological cancers. He is a Chief Investigator of a national randomised placebo-controlled Phase II neo-adjuvant study in muscle invasive bladder cancer. He served as Chief Investigator of various early phase trials, and translational studies. Professor Hussain has authored over 100 peer-reviewed publications including 4 book chapters in textbooks of oncology. His Google scholar H-index is 37 with over 8300 citations. He has published in high impact journals including New England Journal of Medicine, Lancet, Lancet Oncology, JAMA, JAMA Oncology, Journal of Clinical Oncology, European Urology, Annals of Oncology, Clinical Cancer Research, British journal of Cancer.

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