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Dr Simon Crabb is an Associate Professor in Medical Oncology at the University of Southampton with a clinical practice specialising in genitourinary cancers at University Hospital Southampton. His research interests are focussed on the development of novel therapeutic strategies for these diseases. Dr Crabb is the Associate Clinical Director of the Southampton Clinical Trials Unit, Deputy Director of the Southampton Experimental Cancer Medicine Centre and a lead for early phase cancer clinical trials. He is chair of the Genomics England Clinical Interpretation Partnership for bladder cancer, and a member of the NCRI Bladder and Renal Group, the NCRI Prostate Group and the Experimental Medicine Expert Review Panel for Cancer Research UK. Dr Crabb is an active contributor to the UK academic trials portfolio in urological malignancies, including as Chief Investigator on the SPIRE, GUSTO and ProCAID trials, and lead for the rucaparib arm of the ATLANTIS trial.